African Swine Fever (ASF) has plunged Mizoram into a livestock crisis, with 2025 losses forecasted at ₹115 crore. The disease’s ferocity has dismantled pig populations, upending livelihoods in one of India’s most pig-reliant states. Epicenters in southern and central districts reveal a grim pattern: farms report 80-100% mortality rates. The virus, resilient in the environment, persists in meat products and fomites, complicating eradication in Mizoram’s biodiverse landscape. This outbreak serves as a clarion call for systemic reforms, including enhanced funding for veterinary infrastructure and AI-driven outbreak prediction to fortify defenses.